Sustainability & Research

Sustainability is a guiding influence for all of Soul Foundation’s research areas. It is based on a simple principle: Everything that we need for our survival and well-being depends, either directly or indirectly, on our natural environment. To pursue sustainability is to create and maintain the conditions under which humans and nature can exist in productive harmony to support present and future generations.

Sustainability research supports the development of a variety of methods, tools, guidance, and programs that further the application of sustainability within decision-making.

Soul Foundation Water Research

Soul Foundation supports Water Research science and tools necessary to develop sustainable solutions to 21st-century water resource problems, ensuring water quality and availability in order to protect human and ecosystem health. Water is one of our most precious resources. We depend upon it for our livelihoods, healthy ecosystems, and a robust economy. Yet, a host of challenges, such as aging infrastructure, population changes, and security events, threaten the safety and sustainability of our water resources. To address these complex issues, Soul Foundation supports conducting research for innovative scientific and technological solutions that ensure adequate supplies of clean water to protect people’s health and livelihood, to protect and restore watersheds and aquatic ecosystems, and to strengthen our economy.

 

Air Quality Research

Air pollution kills an estimated seven million people worldwide every year. From smog hanging over cities to smoke inside the home, air pollution poses a major threat to health and climate. The combined effects of ambient (outdoor) and household air pollution cause about seven million premature deaths every year, largely as a result of increased mortality from stroke, heart disease, chronic obstructive pulmonary disease, lung cancer, and acute respiratory infections.

Soul Foundation supports air pollution research in three broad areas:

  • Measuring air pollution exposure and effects in humans and ecosystems.
  • Delivering innovative tools and technologies to reduce and prevent harmful emissions.
  • Delivering modeling, monitoring, measurement metrics and critical science information to make decisions regarding air quality to protect public health and the environment.

Medical Research

We’re supporting the brightest minds in the emerging field of exosome research to develop next-generation therapeutics, and to bring economic cures and treatments for diseases that impair the quality of life for millions of people around the globe.

 

Soul Foundation supports bioscience, biotechnology, and research while collaborating to design and engineer the most advanced therapeutics, through deep clinical and regulatory expertise in medicine and pharmaceuticals.

Now is the time to discover, develop, and build foundational structure and understanding that supports advancements, cutting edge technology and research in the ever-evolving field of medicine.  Research is a vital component in understanding our complex and sophisticated bodies. Here we have developed a platform to support research that nurtures and accelerates solutions, which reinforce vitality, vibrant health, healing, and wellbeing.

 

Exosomes are extracellular nanoparticles (30-100nm in diameter) that are important in intercellular (cell-cell) communication and are important in the transmission of macromolecules between cells. They have been known to be useful vectors for drugs because they are composed of cell membranes, rather than synthetic polymers, and are better tolerated by the host.

Studies have established that exosomes are actively secreted by almost all cells through exocytosis, a process by which the contents of a cell are released to the exterior through the fusion of the vacuole membrane with the cell membrane.

 Exosomes can be extracted from all cells and body fluids and they contain multiple proteins, lipids, DNA, RNAs (mRNA, miRNA, ncRNA), and even biomolecules for viruses and prions.

 

These nano-particles have the ability to transfer information in the form of their contents, thus acting as signalosomes, either locally or by traveling to distant tissues wherein they influence various cellular functions. Some of the biological processes, which are regulated by exosomes, are:

 

  • Cell metabolism and signaling
  • Development and regeneration
  • Cell adhesion and motility
  • Immune response, inflammation
  • Exchange of pathogenic proteins/organisms
  • Tumor progression and metastasis
  • Stemness and reprogramming
  • Cardiovascular diseases
  • Neural development, homeostasis, and
    neuro diseases (Parkinson’s, Alzheimer’s and ALS)

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